Cough hypersensitivity syndrome: towards a new approach to chronic cough

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Cough hypersensitivity syndrome: towards a new approach to chronic cough.

Although cough is a highly frequent motive for visiting the doctor among both adults and children in primary care [1, 2], it usually resolves spontaneously within a few days or weeks. Conversely, chronic cough, broadly defined as cough persisting for more than 8 weeks, is often a more difficult clinical situation from both diagnostic and therapeutic perspectives [3]. In many patients, the anato...

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Chronic cough hypersensitivity syndrome

Chronic cough has been suggested to be due to three conditions, asthma, post nasal drip, and reflux disease. A different paradigm has evolved in which cough is viewed as the primary condition characterised by afferent neuronal hypersensitivity and different aspects of this syndrome are manifest in the different phenotypes of cough. There are several advantages to viewing cough hypersensitivity ...

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Chronic cough and obstructive sleep apnoea: reflux-associated cough hypersensitivity?

Obstructive sleep apnoea (OSA) is being increasingly recognised as a cause of chronic cough. The impact of continuous positive airway pressure (CPAP) therapy and the mechanism of this association are not well understood. We describe a patient with OSA and chronic cough who responded well to CPAP. Objective and subjective assessments of cough on treatment with CPAP, off CPAP and on follow-up as ...

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Chronic productive cough: An approach to management

❏ Diagnostic algorithm for patients with chronic productive cough outlined. A chronic 'productive' or 'wet' cough is a common presenting complaint for patients attending the adult respiratory clinic. Most reviews and guidelines suggest that the causes of a productive cough are the same as those of a non-productive cough and as such the same diagnostic pathway should be followed. Although it see...

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Cough that remains unexplained after basic clinical assessment is a common reason for referral to secondary care. Much of the evidence about management of isolated chronic cough is derived from case series; this evidence suggests that isolated chronic cough is usually due to asthma, gastro-oesophageal refl ux disease, and upper airway conditions, and that it can be cured in most people by treat...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2014

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00150614